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Somatic Dysfunction in Osteopathic Family Medicine
60,17 € *
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Prepare for effective practice with the patient-oriented approach of Somatic Dysfunction in Osteopathic Family Medicine, Second Edition . This practical book covers diagnostic work-up, the clinical rationale for osteopathic manual techniques (OMT) for specific diseases and conditions, manipulative techniques for a variety of patient types (psychiatric, pediatric, obstetric, geriatric, and more), and procedures for common conditions encountered in family practice. * Access expert, up-to-date information with the proven resource endorsed by the American College of Osteopathic Family Physicians (ACOFP) and listed as a primary reference for test question writing by the National Board of Osteopathic Medical Examiners. * Broaden your understanding with expert coverage of the philosophy and principles of osteopathic patient care—including patient empowerment, diagnosing somatic dysfunction, the manipulative prescription, viscerosomatic and somatovisceral reflexes, and psychoneuroimmunology. * Take your learning beyond the book with videos available online. * Prepare to work with a wide range of specific patient populations—psychiatric, pediatric, and obstetric patients as well as athletes, surgical patients, and patients at the end of life. * Master procedures for treating conditions commonly encountered in family practice—otitis media, temporomandibular joint pain and dysfunction, upper respiratory infection, lower respiratory tract infection, hypertension, congestive heart failure, gastrointestinal problems, thyroid disease, Parkinson disease, Larson syndrome (functional vasomotor hemiparesthesia syndrome), fibromyalgia/chronic fatigue syndrome, chronic pain and headache, back pain from short leg syndrome and postural imbalance, back pain from postural decompensation in the sagittal plane, and scoliosis. * Access practical information on office set-up, progress notes and coding, and the standardized medical record.

Anbieter: buecher
Stand: 13.07.2020
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Somatic Dysfunction in Osteopathic Family Medicine
60,17 € *
ggf. zzgl. Versand

Prepare for effective practice with the patient-oriented approach of Somatic Dysfunction in Osteopathic Family Medicine, Second Edition . This practical book covers diagnostic work-up, the clinical rationale for osteopathic manual techniques (OMT) for specific diseases and conditions, manipulative techniques for a variety of patient types (psychiatric, pediatric, obstetric, geriatric, and more), and procedures for common conditions encountered in family practice. * Access expert, up-to-date information with the proven resource endorsed by the American College of Osteopathic Family Physicians (ACOFP) and listed as a primary reference for test question writing by the National Board of Osteopathic Medical Examiners. * Broaden your understanding with expert coverage of the philosophy and principles of osteopathic patient care—including patient empowerment, diagnosing somatic dysfunction, the manipulative prescription, viscerosomatic and somatovisceral reflexes, and psychoneuroimmunology. * Take your learning beyond the book with videos available online. * Prepare to work with a wide range of specific patient populations—psychiatric, pediatric, and obstetric patients as well as athletes, surgical patients, and patients at the end of life. * Master procedures for treating conditions commonly encountered in family practice—otitis media, temporomandibular joint pain and dysfunction, upper respiratory infection, lower respiratory tract infection, hypertension, congestive heart failure, gastrointestinal problems, thyroid disease, Parkinson disease, Larson syndrome (functional vasomotor hemiparesthesia syndrome), fibromyalgia/chronic fatigue syndrome, chronic pain and headache, back pain from short leg syndrome and postural imbalance, back pain from postural decompensation in the sagittal plane, and scoliosis. * Access practical information on office set-up, progress notes and coding, and the standardized medical record.

Anbieter: buecher
Stand: 13.07.2020
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Autophagy: Cancer, Other Pathologies, Inflammat...
173,90 € *
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Understanding the importance and necessity of the role of autophagy in health and disease is vital for the studies of cancer, aging, neurodegeneration, immunology, and infectious diseases. Comprehensive and up-to-date, this book offers a valuable guide to these cellular processes whilst inciting researchers to explore their potentially important connections.Volume 5 comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy, the therapeutic inhibition of autophagy in cancer, and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders. In spite of the increasing importance of autophagy in the various pathophysiological conditions mentioned above, this process remains underestimated and overlooked. As a consequence, its role in the initiation, stability, maintenance, and progression of these and other diseases remains poorly understood.This book is an asset to newcomers as a concise overview of the diverse disease implications of autophagy, while serving as an excellent reference for more experienced scientists and clinicians looking to update their knowledge.Volumes in the SeriesVolume 1: Molecular Mechanisms. Elucidates autophagy's association with numerous biological processes, including cellular development and differentiation, cancer, immunity, infectious diseases, inflammation, maintenance of homeostasis, response to cellular stress, and degenerative diseases such as Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis, and prion diseases. Volume 2: Role in General Diseases. Describes the various aspects of the complex process of autophagy in a myriad of devastating human diseases, expanding from a discussion of essential autophagic functions into the role of autophagy in proteins, pathogens, immunity, and general diseases. Volume 3: Role in Specific Diseases. Explores the role of autophagy in specific diseases and developments, including: Crohn's Disease, Gaucher Disease, Huntington's Disease, HCV infection, osteoarthritis, and liver injury, with a full section devoted to in-depth exploration of autophagy in tumor development and cancer, as well as the relationship between autophagy and apoptosis. Volume 4: Mitophagy. Presents detailed information on the role of mitophagy, the selective autophagy of mitochondria, in health and disease, by delivering an in-depth treatment of the molecular mechanisms involved in mitophagy initiation and execution, as well as the role of mitophagy in Parkinson Disease, cardiac aging, and skeletal muscle atrophy. Volume 5: Role in Human Diseases. Comprehensively describes the role of autophagy in human diseases, delivering coverage of the antitumor and protumor roles of autophagy, the therapeutic inhibition of autophagy in cancer, and the duality of autophagy's effects in various cardiovascular, metabolic, and neurodegenerative disorders. Volume 6: Regulation of Autophagy and Selective Autophagy. Provides coverage of the mechanisms of regulation of autophagy, intracellular pathogen use of the autophagy mechanism, the role of autophagy in host immunity, and selective autophagy. Volume 7: Role of Autophagy in Therapeutic Applications. Provides coverage of the latest developments in autophagosome biogenesis and regulation, the role of autophagy in protein quality control, the role of autophagy in apoptosis, autophagy in the cardiovascular system, and the relationships between autophagy and lifestyle. Volume 8: Autophagy and Human Diseases. Reviews recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities, and introduces new, more effective therapeutic strategies, in the development of targeted drugs and programmed cell death, providing information that will aid on preventing detri

Anbieter: Dodax
Stand: 13.07.2020
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Monoamine Transporter Inhibitors
68,00 € *
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Vesicular monoamine transporters (VMAT) are responsible for the uptake of cytosolic monoamines into synaptic vesicles in monoaminergic neurons. In the central nervous system, vesicular monoamine transporter 2 (VMAT2) is the only transporter that moves cytoplasmic dopamine (DA) into synaptic vesicles. Pharmacologically enhancing DA sequestration by VMAT2, and thus preventing the oxidation of DA, may be a strategy for treating diseases such as Parkinson s disease. The neurotoxicity and addictive properties of various psychostimulants have been attributed, at least partly, to their interference with VMAT2 functions. Therefore, VMAT2 may also be a novel target for the development of treatments for psychostimulant abuse. This book summarizes the possible role of VMAT2 as a therapeutic target and the current understanding of the structure-activity relationship of ligands, including tetrabenazine analogs, ketanserin analogs, and 3-amine-2- phenylpropene with VMAT. The molecular structure of VMAT2 and its relevance to ligand binding and the mechanism of transport of these compounds through VMAT are briefly discussed in this book.

Anbieter: Dodax
Stand: 13.07.2020
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Parkinson's Disease
201,70 € *
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Parkinson's Disease, Volume 132 addresses new developments in the F33 study of this disease, highlighting how the lives of people with Parkinson's have undergone dramatic changes in the last decade. New to this edition are chapters on the Hallmarks of clinical aspects PD throughout centuries, The motor syndrome of Parkinson disease, The non-motor features of Parkinson's disease, The New Diagnostic Criteria for Parkinson's disease, Advances in the Clinical Differential diagnosis, Clinical assessments in PD : Scales and monitoring, Biomarkers of Parkinson's disease: an Introduction, and the Genetics of Parkinson's Disease: Genotype-Phenotype Correlations.The topics discussed in this comprehensive series provide a clearer understanding of the prodromal stage, genetics, strategies, routes of treatment, and development of non-dopaminergic therapies in Parkinson's Disease, both medical and surgical.Contains cutting-edge developments in the fieldPresents both motor and non-motor coverage

Anbieter: Dodax
Stand: 13.07.2020
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Contributions of Vision to Gait and Perception ...
59,00 € *
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This book investigated how vision contributes to gait impairment in Parkinson s disease (PD). This was achieved by manipulating visual feedback in the form of step cues, but also from a perceptual standpoint by evaluating how visual perception might contribute to gait impairment. Combining visual feedback aids in perceptually demanding conditions facilitated a greater understanding of the deficits associated with gait in PD. Also, a number of visual cues were examined to determine the viability of these cues in improving the abnormal gait patterns demonstrated by these individuals with PD, including freezing of gait (FOG) and the less severe shuffling step pattern. It was determined that individuals with PD require conscious control of their gait pattern in order to overcome the gait deficits which are prevalent in PD. Also, it was found that a certain degree of visuospatial ability appears to be more greatly affected in thoseindividuals with PD who are subject to FOG. This suggests an important perceptual difference between the PD observed within those who experience FOG and non-FOG individuals with PD.

Anbieter: Dodax
Stand: 13.07.2020
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Parkinson's disease and Mucuna Magic
35,90 € *
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Approximately 200 years ago, James Parkinson had described the major symptoms of a disease that ultimately came to stand his name, i.e. Parkinson's disease (PD). Gradually but definitely, our understanding about the disease has got enhanced, still the effective treatment for the disease has not yet been developed. PD leftovers an enormous challenge to those who suffer from it and to those concerned with its supervision. In addition to the problems common to other disabling neurological conditions, the management of PD must take into account the fact that the foundation of pharmacological treatment, levodopa, can ultimately produce dyskinesia, also called drug induced dyskinesia and motor fluctuation. Moreover, there are a number of agents besides levodopa that can help in the management of PD, and there is tempting but unverified prospect that other treatments might protect against worsening neurological disability. Moreover, in developing countries the marketed levodopa preparation is not accessed by individuals suffering from PD. Thus, a substantial amount of judgement is necessary in tailoring individual therapy and in timing treatment initiation.

Anbieter: Dodax
Stand: 13.07.2020
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miRNAs functional analysis of genes through bio...
55,90 € *
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This study reveals that using the nematode worm C. elegance with enhancing our understanding of functionality of genes. This Caenorhabditis elegans is a model for identification name of targeted genes then select 113 precursors and 26 miRNAs retrieves from miRBase and these miRNAs target 610 genes in human. In this prediction we found exact name of Potential genes with their function and These genes regulate various genomic function with oncogenic transformation, myelogeneous leukemia, Alzheimer's disease, Alzheimer's disease, spinal muscular atrophy, poly cystic kidney disease and muscular dystrophyLoeys-Dietz aortic aneurysm syndrome (LDAS),adermatoglyphia, Parkinson disease,lymphoblastic leukemia, hypervalinemia and hyperleucine-isoleucinemia, giant axonal neuropathy (GAN), Turner's syndrome, Klinefelter's syndrome and Triple X syndrome Color blindness, hemophilia, and Duchenne muscular dystrophy . We hoping this work helpful for young researchers

Anbieter: Dodax
Stand: 13.07.2020
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Isoquinolines And Beta-Carbolines As Neurotoxin...
213,99 € *
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       The specific topic, “Isoquinolines And Beta-Carbolines As Neurotoxins And Neuroprotectants – New Perspectives In Parkinson`S Disease Therapy,” was chosen in light of accumulating neurobiological evidence indicating that, in addition to exogenous neurotoxins (e.g., 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine [MPTP]), endogenous compounds may play an important role in the most common neurodegenerative disorders (e.g., Parkinson`s disease). Two groups of amine related compounds, which appeared chemically like MPTP, were detected in human brain and cerebrospinal fluid (CSF): ß-carbolines (BCs) and tetrahydroisoquinolines  (TIQs). These are heterocyclic compounds formed endogenously from phenylalanine/tyrosine (TIQs) and tryptophan, tryptamine, and 5-hydroxytryptamine (BCs), respectively and exert a wide spectrum of psychopharmacological and behavioral effects. The TIQs and BCs may bind to their own high affinity sites on neuronal membranes associated with or located close to the receptors of neurotransmitters. Research on TIQs and BCs is stimulated also by their possible role in pathological conditions, especially parkinsonism and alcoholism. Recently, clinical interest has been spurred by their role as neuroprotective, and even neurorestorative, anticonvulsant and antiaddictive, substances.             In this book we are going to summarize, for the first time, the results from behavioral, neurochemical and molecular experiments, which demonstrate a wide spectrum of TIQs and BCs effects - from their rather mild neurotoxic actions to the important neuroprotective and antiaddictive properties. Additionally, the recent results of experimental studies in vivo have allowed a much better understanding and simultaneous comparison of the neurochemical and molecular mechanisms underlying the neuroprotective and neurotoxic actions of endogenous TIQs and BCs and have pointed to the possibility of their therapeutic applications in neurodegenerative diseases such as Parkinson's disease.

Anbieter: Dodax
Stand: 13.07.2020
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